Job Opening at Pfizer: Immune Assay Scientist

Pfizer

Immune Assay Scientist (Non-PhD)                                                                                                                                       Location: La Jolla, California                                                                                                                                                          Visit http://www.pfizercareers.com and apply to job ID 1009691 

All over the world, Pfizer colleagues are working together to positively impact health for everyone, everywhere. Each position at Pfizer touches and contributes to the success of our business and our world. That’s why, as one of the global leaders in the biopharmaceutical industry, Pfizer is committed to seeking out inspired new talent who share our core values and mission of making the world a healthier place.

Role Description:

Vaccine Immunotherapeutics seeks to discover novel vaccines (prophylactic and therapeutic) for the prevention and treatment of significant human diseases, using a variety of vaccine technology platforms in combination with immunomodulatory agents. We are searching for a motivated individual with flow cytometry experience to join our Immunology group. The candidate will be required to have experience in the culture of immune cells and in the routine setup and execution of immunoassays – in particular the intracellular cytokine staining of T cells for the measurement of vaccine-induced cellular responses. The candidate will be required to proactively apply their knowledge to design experimental work plans with their supervisor and effectively conduct their work both independently and as a member of a matrix team. The candidate will be required to summarize and critique their results, with support from their supervisor, as well as communicate data concisely at team and departmental meetings.

This role is primarily laboratory based with a major emphasis placed upon implementing state-of-the-art immunologic techniques, and routinely conducting high-quality assay work in an organized and safe manner.

Laboratory and related work (~80% of time) with minimal supervision: • Run a variety of immune cell-based immunoassays with samples generated from vaccine project studies (including studies with large sample numbers >100). • Perform flow cytometry assays for immune cell profiling (ICP) and intracellular cytokine staining (ICCS) using fluorochrome panels >6 colors (assay setup, acquisition and analysis) • Define study aims and experimental plans with supervisor and then execute the work following the agreed plans (independently once familiar with the area of work, or as part of a team effort). • Identify and report any experimental problems, troubleshoot causative factors, and implement necessary corrections following discussion with peers and/or supervisor. • With support of their supervisor, analyze and interpret experimental data and prepare presentations for project meetings. • Regularly record experimental work upon completion in electronic notebook systems and archive instrument raw data in server databases. • Assist in the day-to-day running of the laboratory by ordering and preparing reagents and maintaining equipment, as required.

Communication:

• Actively contribute ideas and challenge data at Immunology line and project team meetings. • Provide clear, concise and timely responses to project team requests for data and experimental information. • Develop and refine presentation skills by regularly presenting data at internal meetings.
Safety: • Comply with all EH&S regulations and safe laboratory practices and act as a vigilant advocate for the safety of fellow colleagues. • Identify and act to reduce hazards and risks in the laboratory through use of Risk Assessments and Job-based Hazard Assessments.

Qualifications:

• B.Sc. in life sciences, preferably including coursework in immunology.
• 3+ years’ experience working in a relevant laboratory setting that routinely performs cellular immunoassays, including flow cytometry, to characterize immune responses.

Preferred: 

• Work experience primarily based in biotech/pharmaceutical industry settings and focused around areas of vaccine development. • Practical experience with the processing of murine splenocytes and/or human blood samples

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