The 16th Annual MedChem Symposium – Friday, July 12th

The 16th Annual MedChem Symposium is on July 12th! Registration is now open! Please visit http://chemistry.ucsd.edu/go/medchem for more info!

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Brown University: Visiting Lecturers in Chemistry

We seek your assistance of our efforts to identify qualified candidates for two visiting lecture positions in Chemistry at Brown for the 2013-14 academic year.

One lecturer will be responsible for instructing the General Chemistry sequence. A second lecturer will instruct the Organic Chemistry sequence. Detailed information can be found on the landing page of the job posting: https://secure.interfolio.com/apply/21681.

Lab Asssistant Position

Pacific Integrated Energy is looking for a new lab assistant intern!
Pacific Integrated Energy is a start up company focused on the application of plasmonics and nanophotonics to solar energy.
Position Description: We have opportunities for students interested in working in a lab environment collecting data characterizing optical devices.

Required skills/experience:
Experience with electrical and optical measurements:  Required
Physics, chemistry or engineering lab experience:  Required
LabView Experience:  Desirable
Wet lab chemistry experience:  Desirable
Internship Period: Flexible
Compensation: Paid
Internship Location: Carmel Valley Area and UCSD Campus
Contact name: Mr. Michael Fennell

Contact email: mf@pienergy.com

Merck-Wolfe Laboratories Postdoctoral Fellowship

JOB SUMMARY:
Merck Research Laboratories and Wolfe Laboratories have created a unique postdoctoral
fellowship program. In this highly competitive and challenging program, the
postdoctoral fellow is expected to conduct basic biopharmaceutics research as well as
perform applied R&D. For the basic research project, the successful candidate will be
mentored by Merck scientists on research that is expected to generate peer-reviewed
publications. For the applied R&D projects, the successful candidate will work with the
Wolfe scientific team to advance our clients’ programs from discovery into early clinical
development. The postdoctoral fellow will work at Wolfe Laboratories’ Watertown, MA
facility.

An understanding of the phenomena governing intestinal absorption of drugs following
oral administration is a topic of great interest to both academia and industry. The
successful candidate will utilize physical chemistry, pharmaceutics and solid-state
chemistry, with a goal of better understanding the mechanistic underpinnings of variable
drug absorption as a function of physicochemical properties. Wolfe Laboratories seeks a
PhD scientist who will be responsible for the advancement of structure-based approaches
to effectively design solid forms for optimal drug product performance, the identification
of pharmaceutically-relevant forms through comprehensive polymorph/solvate
crystallization screening, and the assessment of relevant physicochemical properties in
support of form selection. Several known or hypothesized formulation and release
mechanisms will be interrogated, including amorphous solid dispersion supersaturation,
precipitation of drug from formulation vehicles or gastric media (i.e., weak bases), and
drug release kinetics from hydrophilic (e.g., polyethylene glycol) and lipid (e.g., mono-,
di-, and triglyceride) systems. The scientist must have a thorough knowledge of the
thermodynamics of drug crystal forms needed to elucidate their phase relationships, a
broad understanding of the application of designer solid forms and super saturation
strategies for solubilization, and of crystal nucleation and growth kinetics needed to
optimize solid form evaluations. The ultimate goal shall be to predict relative
pharmacokinetic performance and variability in animals using calculated and measured
properties of drug compounds and their formulations.
Collaboration is at the core of our success. The successful applicant will be a key member
of the team and will be responsible for understanding dissolution and absorption
characteristics of drug forms and formulations. The candidate will utilize a wide range of
in vitro, in situ, and in vivo techniques to achieve this goal. Creativity and innovation,
built on sound technical knowledge and excellent problem-solving skills, are required in
order to meet the challenges posed by today’s new chemical entities.

DUTIES AND RESPONSIBILITIES:
SCIENTIFIC RESPONSIBILITIES:
• Identify and leverage state-of-the-art technologies to design crystal forms (crystal
engineering) and crystallization processes (particle engineering)
• Lead, design and/or conduct crystallization screens for drug crystal forms,
including salts, cocrystals, polymorphs and solvates
• Leverage a variety of physical-chemical characterization techniques to identify
novel crystal forms and to assess relevant physical properties in support of crystal
form selections for drug products
• Design strategies and implement best business practices for comprehensive solid
form (salt, polymorph) screening and selection
• Develop a thorough understanding of the CM&C development strategy with
respect to physicochemical properties and formulation development
• Provide effective technical leadership to integrated drug substance and drug
product development teams
• Ensure understanding and adherence to applicable laboratory quality systems.
• Adopt good documentation practices by properly documenting experiments and
writing high quality technical reports
• Provide mentoring and develop the technical breadth/depth of associate-level
scientists responsible for crystallization screening and formulation development
• Serve as a corporate technical resource in the chemistry of pharmaceutical solids
(polymorphism, crystallization, X-ray diffraction, thermal analysis, moisture
sorption analysis, solubility, microscopy, etc.)
• Perform laboratory experiments related to the above.
• Create publications and presentations for outside scientific meetings and
conferences to showcase Wolfe Laboratories’ scientific leadership in the field of
small molecule analysis, characterization and formulation development.

CLIENT INTERACTION RESPONSIBILITIES:
• Interface with clients to develop an in-depth understanding of client objectives
and define solutions to meet their program requirements
• Develop compelling approaches and solutions to address client needs
• Write persuasive proposals for the projects
• Regularly interact with clients to keep them abreast of project progress
• Write and review interim and final reports.

REQUIRED BACKGROUND AND EXPERIENCE:
• PhD in Organic, Physical or Analytical Chemistry, Pharmaceutical Chemistry,
Chemical Engineering, or a related field
• Up to 5 years of relevant experience in academic or pharmaceutical solid state
chemistry
• Deep technical knowledge/expertise in organic solid-state chemistry
(crystallization, thermodynamics, solid-state characterization) and/or
pharmaceutical sciences
• Relevant experience in crystallization, physical characterization techniques (i.e.,
thermal and moisture sorption analyses, microscopy, chromatography, solubility,
powder and single crystal X-ray crystallography, solid-state NMR spectroscopy)
and dissolution and/or crystal modeling
• Outstanding written and oral communication skills as well as polished and
persuasive client presentation skills
ADDITIONAL DESIRABLE BACKGROUND:
• Expertise in computational solid-state chemistry (crystal structure prediction,
structure solution from XRPD data, structure-property prediction, molecular
dynamics simulations, SSNMR chemical shift prediction)
Interested candidates are requested to email a copy of their resume with a cover letter
including salary history to: steve.pangione@wolfelabs.com
Wolfe Laboratories, Inc. (WLI), located in Watertown, MA, is a premier contract
research organization that provides integrated early drug development solutions to the
biopharmaceutical industry. Wolfe Laboratories is an essential element of the drug
development ecosystem, recognized by global and virtual biopharmaceutical companies
as a science-driven organization whose mission is to provide outstanding discovery and
development services tailored to its clients’ needs for rational formulation development.
Wolfe Laboratories integrates the critical path components of early development to
ensure that programs advance while meeting rigorous scientific demands with flexibility
to address dynamic challenges and aggressive timelines. Wolfe Laboratories’ vision is to
improve human health, and we continue to strive towards that goal by embracing our core
values of integrity, excellence and teamwork. The company has a high percentage of
repeat clients, which is a testament to its long-term commitment of continual investment
in its capabilities to meet biopharma’s growing demand for high quality, integrated early
development services.
We have a steady 14-year track record of growth, success and profitability.
For more information visit us at: http://www.wolfelabs.com.
Wolfe Laboratories, Inc is an Equal Employment Opportunity employer.

 

 

 

Live Chat with AAAS S&T Policy Fellows

AAAS S&T Policy Fellows     2014-15 Application Deadline: Nov. 1, 2013

The online application for the 2014-15 AAAS S&T Policy Fellowships is now open! Would you like to hear more about Fellowship experience? Have your questions answered live by Fellows and program staff at our next online chat event!

Event Date: June 6, 2013 | Live 2:00 – 3:00 p.m. EDT
Register: bit.ly/XC01a4
How: Register online or tweet to #AAASLive
Who: You, current, Alumni Fellows and Fellowship Staff
What: Make valuable contributions and apply your experience in new ways. Join us to discuss:

  • Details of the online application process
  • Eligibility criteria
  • How different disciplinary areas can contribute and gain from the fellowship
  • What Fellows actually “do” during their fellowship year
  • Career paths Fellows take after completing the program
  • Anything fellowship related!

You can submit questions early by sending an email. You can also join the conversation on Twitter with #AAASLive. See the event website for more information: http://membercentral.aaas.org/events/aaas-live-st-policy-fellows

The live event is open to all.

New Application Deadline: November 1, 2013, 5:00 p.m. EST – https://fellowshipapp.aaas.org

 

UCSD Career Boost Camp: Innovation, Entrepreneurship, & Your Career!

Hear from Robin Ryan, “America’s Top Career Expert,” and author of “60 seconds and you’re hired!” featured on “Oprah” and “Dr. Phil” and a panel of entrepreneurs, moderated by Reo Carr (Editor-in-Chief, San Diego Business Journal ) at Career Boost Camp 2013, during Alumni Weekend. 

>From a Chief Creative Officer to a Venture Capitalist, a panel of distinguished UCSD alumni will provide valuable insights to take your career and life to the next level, and inspire you to IMAGINE MORE! 

The first 5 graduate students to email me directly will get in free and put on my special invite list.

Saturday, June 8, 10-1, Rady School of Management

For event details and to register, space is limited, (ends May 31) visit: http://tinyurl.com/nfjt92v

Career Boost Camp alumni.ucsd.edu

 

UCSD Students with Children, Info Session 5/21

Info session for Grad Parents Network:

Tuesday, May 21, 3:00-4:00pm

Bear Room in the Price Center (upstairs); food will be provided by Cafe Roma

Graduate students: We are recruiting new members and officers, signing people up on our emailing list, providing information on new resources for GSRs with children, and other resources currently available to all grad students.

Undergraduate students: We will also reach out to current undergrads with children to answer questions about grad life as a parent.

Thank you!

Jennifer (Grad Parent Network, principal member)